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List of AquaFlux User Publications

The publications listed below are from our customer labs and feature AquaFlux measurements used in diverse areas of research. Click on the More.. link to read the abstract and download the full text from the publisher's website.

Transepidermal water loss for probing full-thickness skin barrier function: Correlation with tritiated water flux, sensitivity to punctures and diverse surfactant exposures.
Elmahjoubi, E. Frum, Y. Eccleston, G.M. Wilkinson, S.C. and Meidan, V.M. Toxicology in Vitro, 23(7), 1429-35, 2009. (More..).

In vivo transungual iontophoresis: Effect of DC current application on ionic transport and on transonychial water loss.
Dutet, J. and Delgado-Charro, M.B. Journal of Controlled Release, 140(2), 117-25, 2009. (More..).

Correlation of transepidermal water loss with skin barrier properties in vitro: Comparison of three evaporimeters.
R. Elkeeb, X. Hui, H. Chan, L. Tien and H.I. Maibach. Skin Research and Technology, in press. (More..).

Measuring transepidermal water loss: "Comparative in vivo study of condenser-chamber, unventilated-chamber and open-chamber systems.
S. Farahmand, L. Tien, X. Hui and H.I. Maibach. Skin Research and Technology, 15(4), 392-398, 2009.

Preparation and in vitro evaluation of topical formulations based on polystyrene-poly-2-hydroxyl methacrylate nanoparticles.
X. Wu, P. Griffin, G.J. Price, R.H. Guy. Molecular Pharmaceutics, 6(5), 1449–1456, 2009.

Drug delivery to the skin from sub-micron polymeric particle formulations: Influence of particle size and polymer hydrophobicity.
X. Wu, B. Biatry, C. Cazeneuve and R.H. Guy. Pharmaceutical Research, 26(8), 1995-2001, 2009.

Improved bioequivalence assessment of topical dermatological drug products using dermatopharmacokinetics.
B. N'Dri-Stempfer, W.C. Navidi, R.H.Guy and A.L.Bunge. Pharmaceutical Research, 26(2), 316-28, 2009.

Dermatopharmacokinetics of betamethasone 17-valerate: Influence of formulation viscosity and skin surface cleaning procedure.
S. Wiedersberg, C.S. Leopold and R.H.Guy. European Journal of Pharmaceutics and Biopharmaceutics, 71(2), 362-366, 2009.

Dye diffusion from microcapsules with different shell thickness into mammalian skin.
H.N. Yow, X. Wu, A.F. Routh and R.H. Guy. European Journal of Pharmaceutics and Biopharmaceutics, 72(1), 62-68, 2009.

Pharmacodynamics and dermatopharmacokinetics of betamethasone 17-valerate: assessment of topical bioavailability.
S. Wiedersberg, A. Naik, C.S. Leopold and R.H. Guy. British Journal of Dermatology, 160(3), 676-86, 2009.

Transcutaneous immunisation assisted by low-frequency ultrasound.
A. Dahlan, H.O. Alpar, P. Stickings, D. Sesardic and S. Murdan. International Journal of Pharmaceutics, 368(1-2), 123-128, 2009.

Dermatopharmacokinetics: Factors Influencing Drug Clearance from the Stratum Corneum.
S. Nicoli, A.L. Bunge, M.B. Delgado-Charro, and R.H. Guy. Pharmaceutical Research, 26(4), 2009.

Effects of Various Vehicles on Skin Hydration in vivo.
S. Wiedersberg, C.S. Leopold and R.H. Guy. Skin Pharmacol Physiol, 22, 128-130, 2009.

Increased basal transepidermal water loss leads to elevation of some but not all stratum corneum serine proteases.
R. Vögeli, A.V. Rawlings, S. Doppler and T. Schreier. International Journal of Cosmetic Science, 30, 435-442, 2008.

Serine proteases, skin function and homeostasis.
R. Vögeli, A.V. Rawlings, J.W. Fluhr, S. Doppler and T. Schreier. 25th IFSCC Congress, 6-9 October, Barcelona, Spain, 2008.

A few aspects of transonychial water loss (TOWL): Inter-individual, and intra-individual inter-finger, inter-hand and inter-day variabilities, and the influence of nail plate hydration, filing and varnish.
S. Murdan , D. Hinsu, M. Guimier. European Journal of Pharmaceutics and Biopharmaceutics, 70, 684-689, 2008.

The determination of stratum corneum thickness: An alternative approach.
L.M. Russell, S. Wiedersberg, M. Begoña Delgado-Charro. European Journal of Pharmaceutics and Biopharmaceutics, 69(3), 2008.

Correlation of transepidermal water loss with skin barrier function In vitro and comparison of three evaporimeters.
R. Elkeeb, X. Hui, H. Chan, L. Tian, H.I. Maibach. UC Systemwide Bioengineering Symposium in Riverside, CA, 2008.

Measuring transepidermal water loss: A comparison between conventional bioengineering techniques in vivo.
S. Farahmand, L. Tien, X. Hui and H.I. Maibach. 9th Annual UC Systemwide Bioengineering Symposium, Riverside, CA, June 20-22nd, 2008.

Techniques to characterise skin permeability.
M. Machado, T. Salgado, H. Ribeiro, J. Hadgraft and M.E. Lane. Skin Forum. London, UK, 2008.

Guidance for TEWL measurements.
H. Taylor. In: Principles and Practice of Skin Toxicology, (R.P. Chilcott & S. Price eds). Print ISBN: 9780470511725 Online ISBN: 9780470773093. John Wiley & Sons Ltd 2008.

Novel beads made of alpha-cyclodextrin and oil for topical delivery of a lipophilic drug.
L. Trichard, M. Begoña Delgado-Charro, R.H. Guy, E. Fattal and A. Bochot. Pharmaceutical Research, 25(2), 2008.

Microbial colonization of an in vitro model of a tissue engineered human skin equivalent - a novel approach.
D.B. Holland, R.A. Bojar, A.H.T. Jeremy, E. Ingham, K.T. Holland. FEMS Microbiology Letters, 279(1), 2008.

Microbial colonization of an in vitro model of a tissue engineered human skin equivalent – a novel approach.
D.B. Holland, R.A. Bojar, A.H.T. Jeremy, E. Ingham and K.T. Holland. FEMS Microbiology Letters, 279(1), 110-115. Published Online: 11 Dec 2007.

Pharmaceutical compositions comprising metals for modulating epithelial cell-to-cell adhesion.
Patent Wo/2007/020479, York Pharma plc (2007).

Measurements of trans-onychial water loss (TOWL) using Aquaflux.
D. Hinsu and S. Murdan. AAPS Journal, 9, S2, Abstract T3182, 2007.

Profiling of serine protease activities in human stratum corneum and detection of a stratum corneum tryptase-like enzyme.
R. Vögeli, A.V. Rawlings, S. Doppler, J. Heiland and T. Schreier. International Journal of Cosmetic Science, 29(3), 191-200, 2007.

Measurements of trans-onychial water loss (TOWL) using a specially designed cap with the Aquaflux.
D. Hinsu, M. Guimier and S. Murdan. Pharmaceutical Posters on the Web, 2(2), 2007.

Estudi de la formació de nano-emulsions de fase externa aquosa i solubilització de fàrmacs lipòfils.
N. Sadurní Gràcia, PhD Thesis, Universitat de Barcelona. ISBN B.19402-2007 / 978-84-690-4894-8 (2007).

Permeation of 4-cyanophenol and methyl paraben from powder and saturated aqueous solution through silicone rubber membranes and human skin.
W.J. Romonchuk and A.L. Bunge. Journal of Pharmaceutical Sciences, 95(11), 2526 - 2533, 2006.

Closed chamber and open chamber TEWL measurement: A comparison of Dermalab and AquaFlux AF102 instruments.
C. Jones, S. Bennett and J.R. Matheson. Skin Research and Technology (Abstract) 11(4): 296, 2005.

Comparison of three TEWL instruments for in vitro and in vivo measurements.
W. Tian. Skin Resesrch and Technology (Abstract) 11(4): 299, 2005.

 

       

 
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